Fig 5.
Immune-related gene expression in bladder tissues. The expression of immune-related gene mRNA in bladders from vehicle-treated or PUC-treated CPP-injured mice. Relative mRNA expression was measured as the mRNA level in bladder tissue from naïve mice (no any treatment) was set as 1. The expression of COX-2 (A), iNOS (B) and IL-6 mRNA (C) is bladder tissues of vehicle control and PUC-treated mice 24 h after CPP treatment. Data are presented as mean ± SD, and significance was calculated by a paired Student’s t-test. *P<0.05 versus the vehicle control.
CPP: cyclophosphamide; IL: interleukin; iNOS: inducible nitric oxide synthase; PUC: porcine urothelial cell.