Table III.

Univariate analysis of factors associated with overall survival.

Variable	Hazard ratio (95% CI)	P-value
Age at diagnosis (≥60 vs. <60 years)	0.762 (0.568–1.214)	0.113
Sex (male vs. female	2.235 (0.714–7.233)	0.124
Tumor laterality (left vs. right)	1.436 (0.346–5.941)	0.617
miR-183 expression (high vs. low)	2.433 (1.105–5.833)	0.043
miR-96 expression (high vs. low)	1.375 (1.915–3.122)	0.048
miR-182 expression (high vs. low)	1.892 (1.332–3.437)	0.039
Histological grade (G3/G4 vs. G1/G2)	2.564 (1.142–5.760)	0.023
Pathological stage (III/IV vs. I/II)	1.840 (1.056–3.301)	0.034
Metastasis status (M1 vs. M0)	1.245 (0.860–1.903)	0.392
Tumor stage (T3/T4 vs. T1/T2)	1.609 (1.583–1.859)	0.022
Lymph node status (N1 vs. N0)	1.188 (1.292–2.563)	0.021

The median expression level of miRNAs (3.45) was used as the cutoff value between high and low expression. CI, confidence interval; miR, microRNA