Table IV.

Multivariate analysis of factors associated with overall survival.

Variable	Hazard ratio (95% CI)	P-value
miR-183 expression (high vs. low)	5.126 (2.385–11.021)	<0.001
miR-96 expression (high vs. low)	2.078 (0.464–3.138)	0.061
miR-182 expression (high vs. low)	1.312 (0.508–3.132)	0.070
Histological grade (G3/G4 vs. G1/G2)	2.556 (1.139–5.736)	0.023
Pathological stage (III/IV vs. I/II)	1.160 (0.282–4.769)	0.837
Metastasis status (M1 vs. M0)	1.819 (0.961–3.274)	0.068
Tumor stage (T3/T4 vs. T1/T2)	1.713 (1.067–3.033)	0.028
Lymph node status (N1 vs. N0)	2.230 (1.774–3.118)	0.045

The median expression level of miRNAs (3.45) was used as the cutoff value between high and low expression. CI, confidence interval; miR, microRNA