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. 2019 Feb 12;17(4):2465–2472. doi: 10.3892/etm.2019.7256

Figure 6.

Figure 6.

PI3K inhibition enhanced the ability of miR-125a to suppress PI3K/Akt/mTOR signalling pathway activity in an in vitro model of thyroiditis. Relative quantification of (A) PI3K, (B) p-Akt and (C) p-mTOR levels was calculated from western blot analysis results. (D) Western blot analysis of PI3K, p-Akt and p-mTOR levels. Data are expressed as the mean ± standard deviation of independent experiments (n=3). **P<0.01 vs. miR-125a; ##P<0.01 vs. control group. miR-125a, microRNA-125α; PI3K, phosphoinositide 3-kinase; Akt, protein kinase B; mTOR, mechanistic target of rapamycin; p-, phosphorylated.