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. 2019 Mar 19;39(7):e00577-18. doi: 10.1128/MCB.00577-18

FIG 2.

FIG 2

miR-551a inhibits the expression of FAK and targets its 3′ UTR. (A) Western blots showing the expression of FAK in concentration-dependent transfection of miR-551a and expression of miR-551a by qPCR. (B) Increased expression of FAK with miR-551a inhibitor (inh) transfection (*, P = 0.0139; **, P = 0085; n = 3). (C) Bar graphs representing the relative luciferase activity (normalized to that of firefly luciferase) of the 3’ UTR wild type (WT) or a 3′ UTR deletion mutant (UTR Del) upon cotransfection with empty vector or miR-551a (n = 3; *, P values of 0.0136 and 0.0320 for MDA-MB-231 and ZR75 cell lines, respectively; ns, not significant, by one-way analysis of variance).