Table IV.

Interaction between potential risk factors and baseline FMD for incident hypertension

Parameter	FMD			P-value (interaction)
	T3 (5.5–6.8%)	T2 (4.2–5.4%)	T1 (2.8–4.1%)
< 60 years	Ref	1.06 (0.94–1.11)	1.11 (0.98–1.22)	< 0.001
≥ 60 years	Ref	1.09 (0.97–1.15)	1.16 (1.02–1.24)
Female	Ref	0.98 (0.92–1.14)	1.01 (0.95–1.09)	0.031
Male	Ref	1.04 (0.95–1.13)	1.08 (1.01–1.19)
Non-smoker	Ref	0.95 (0.89–1.04)	0.97 (0.93–1.07)	0.165
Smoker	Ref	1.02 (0.97–1.12)	1.06 (0.99–1.14)
Systolic BP < 130 mm Hg	Ref	1.04 (0.97–1.16)	1.07 (0.99–1.19)	< 0.001
Systolic BP ≥ 130 mm Hg	Ref	1.06 (0.99–1.18)	1.12 (1.06–1.23)
eGFR < 90 ml/min/1.73 m2	Ref	1.01 (0.90–1.06)	1.03 (0.95–1.10)	0.306
eGFR ≥ 90 ml/min/1.73 m2	Ref	0.98 (0.92–1.11)	1.01 (0.95–1.14)
Hs-CRP < 3mg/dl	Ref	0.96 (0.90–1.02)	0.99 (0.93–1.08)	0.028
Hs-CRP ≥ 3 mg/dl	Ref	1.02 (0.98–1.15)	1.09 (1.02–1.17)

eGFR – estimated glomerular filtration rate, hs-CRP – high sensitivity C-reactive protein, Ref – reference.