Table I.
Characteristics of groups in terms of the main risk factors for stroke
| Risk factor | Statin group (n = 181) | Non-statin group (n = 153) | P-value |
|---|---|---|---|
| Age, median, range [years] | 80, 70–85# | 78, 72–84# | 0.384* |
| Gender, n (%): | |||
| Male | 59 (32.6) | 39 (25.5) | 0.155* |
| Female | 122 (67.4) | 114 (74.5) | |
| Arterial hypertension, n (%) | 162 (89.5) | 137 (89.5) | 0.995* |
| Ischemic heart disease, n (%) | 111 (61.3) | 90 (58.8) | 0.694* |
| Previous myocardial infarction, n (%) | 28 (15.5) | 26 (17) | 0.811* |
| Diabetes mellitus, n (%) | 64 (37.4) | 46 (31.1) | 0.329* |
| Smoking, n (%) | 29 (16.1) | 26 (17.2) | 0.863* |
| Previous stroke, n (%) | 41 (22.7) | 27 (17.9) | 0.454* |
| Number of strokes, n (%): | |||
| 1 | 29 (16.1) | 20 (13.2) | 0.450* |
| 2 | 8 (4.4) | 5 (3.3) | 0.527** |
| 3 | 3 (1.7) | 4 (2.6) | 0.435** |
| Previous transient ischemic attack, n (%) | 8 (4.4) | 4 (2.7) | 0.782** |
| Previous anticoagulants, n (%) | 12 (6.7) | 6 (4) | 0.673** |
| Previous antiaggregants, n (%) | 68 (37.6) | 65 (42.9) | 0.886* |
| Previous anti-diabetic drugs, n (%) | 45 (24.9) | 37 (24.2) | 0.494* |
| Previous antihypertensives, n (%) | 101 (55.8) | 127 (83) | 0.991* |
| Lipids profile (min.-max.; mean ± SD) [mg/dl]: | |||
| Total cholesterol | 84–298; 176.5 ±40.87 | 82–318; 178 ±43.79 | 0.003*** |
| LDL cholesterol | 30–224; 106.6 ±34.61 | 32–252; 108 ±36.78 | < 0.001*** |
| HDL cholesterol | 12–118; 48.9 ±16.40 | 21–114; 47.5 ±14.89 | 0.472*** |
| Triglycerides | 36–284; 108.9 ±42.05 | 39–394; 109.7 ±46.11 | < 0.001*** |
| BMI (min.–max.; mean ± SD) [kg/m2]: | |||
| Male | 17–45; 27.8 ±7.27 | 18–30.5; 23.9 ±4.21 | 0.081* |
| Female | 18–42.3; 27.4 ±5.71 | 18–45; 28.2 ±5.83 | 0.343* |
| ICA significant stenosis, n (%) | 26 (14.8) | 20 (13.8) | 0.880* |
| Therapeutic INR, n (%) | 10 (5.5) | 6 (3.9) | 0.801** |
#
Quartiles Q1–Q3;
*
Mann-Whitney U test;
**
exact Fisher test;
***
Student’s t-test.