Table II.
Values of laboratory investigations of inflammatory markers and fibrinolytic parameters at inclusion in the study in patients with superficial vein thrombosis treated with dalteparin 10 000 IU (group A) and dalteparin 5000 IU (group B) (values are given as mean ± SD)
Parameter | Group A (n = 35) | Group B (n = 33) | P-value |
---|---|---|---|
Fibrinogen [g/l] | 4.2 ±1.1 | 3.8 ±1.2 | 0.141 |
D-dimer [ng/ml] | 956 ±1019 | 863 ±1215 | 0.733 |
HsCRP [mg/l] | 13.2 ±10.2 | 14.1 ±13.7 | 0.745 |
IL-6 [ng/l] | 3.7 ±3.1 | 3.9 ±3.2 | 0.755 |
IL-8 [ng/l] | 19.3 ±13.8 | 26.2 ±22.0 | 0.125 |
IL-10 [ng/l] | 0.7 ±0.6 | 0.5 ±0.5 | 0.132 |
TNF-α [ng/l] | 2.6 ±6.4 | 2.1 ±1.9 | 0.680 |
t-PA [IU/ml] | 0.8 ±0.3 | 0.8 ±0.3 | 0.899 |
PAI-1 [IU/ml] | 6.3 ±5.4 | 4.7 ±4.6 | 0.182 |
SD – standard deviation, hsCRP – high-sensitivity C-reactive protein, IL-6 – interleukin 6, IL-8 – interleukin 8, IL-10 – interleukin 10, TNF-α – tumor necrosis factor α, t-PA – tissue plasminogen activator, PAI-1 – plasminogen activator inhibitor-1.