FIGURE 2.
Comparison of the teneurin scaffold and peripheral domains with the TcB-TcC complex. (A) Chicken Ten2 (left) is shown in the same orientation as the TcB-TcC complex (right), with structurally equivalent regions colored accordingly (green and yellow: YD repeats, cyan: NHL domain and β-propeller, dark blue: FN-plug and SpvB domain). (B) The YD-repeat regions of both proteins, illustrating the larger size of the shell in TcB-TcC. (C) Structural alignment of the teneurin (gray) and TcC (green) Rhs-associated core-like domain at the autoproteolytic cleavage site of TcC.
