. 2019 Mar 4;2019:5028512. doi: 10.1155/2019/5028512

Table 4.

Receiver operating characteristic curve analysis of pleural effusion cell free DNA in diagnosis of parapneumonic effusion and its sensitivity and specificity with suggested cut-off value.

	AUC	P value	95% confidence interval		Cut off value	Sensitivity	Specificity
	AUC	P value	Lower limit	Upper limit	Cut off value	Sensitivity	Specificity
Nucleus DNA(p) (ng/ml)	0.945	<0.001^∗	0.879	1.000	134.9	0.96	0.81
Mitochondrial DNA(p) (ng/ml)	0.889	<0.001^∗	0.769	1.000	17.8	0.96	0.81
Nucleus DNA(s) (ng/ml)	0.804	0.002^∗	0.660	0.948	41.8	0.86	0.69
White blood cell count (p) (×10⁶/L)	0.893	0.002^∗	0.758	1.000	1.285	0.81	0.90
Neutrophil(p) (%)	0.845	0.007^∗	0.658	1.000	58	0.80	0.90
White blood cell count (s) (×10⁹/L)	0.757	0.007^∗	0.591	0.924	11.5	0.77	0.75
Neutrophil(s) (%)	0.645	0.132	0.461	0.829	81	0.64	0.69

AUC: area under curve; DNA: deoxyribonucleic acid; (s): serum; (p): pleural fluid; ^∗P < 0.05.