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Plaque composition in a severe plaque of a E3L and E3L.GK+/− mouse. Representative images of HPS staining, Movat staining, Sirius Red staining for collagen, immunostaining with α-actin for SMCs, and immunostaining with Mac-3 for macrophages. The arrows depict necrotic areas, including cholesterol clefts. HPS: hematoxylin-phloxine-saffron; SMCs: smooth muscle cells.
