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SIRT1 silencing inhibits epithelial-mesenchymal transition in U87 cells. The (A) mRNA and (B) protein levels of E-cadherin, β-catenin, fibronectin and vimentin in U87 cells following transfection with SIRT1-siRNA were determined using the reverse transcription-quantitative polymerase chain reaction and western blotting, respectively. **P<0.01 and ***P<0.001. siRNA, small interfering RNA; SIRT1, silent information regulator 1; E-cadherin, epithelial cadherin.
