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. 2019 Feb 19;17(4):3842–3850. doi: 10.3892/ol.2019.10052

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Copyright: © Huang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Inhibitory effects of luteolin on the proliferation and invasion of human breast cancer cells. (A) Dose-dependent antitumor effect of luteolin on MDA-MB-231 breast cancer cells after 24 h. Data are presented as the means ± standard deviation (n=3). (B) Luteolin exhibited a significant antitumor effect on the MDA-MB-231 cell line in colony formation assays. (C) Luteolin inhibited cell invasion of MDA-MB-231 cells as detected by a Transwell assay. *P<0.05 vs. the control group (0 µM luteolin); #P<0.05 vs. the 10 µM luteolin group. IC50, half maximal inhibitory concentration.