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. 2019 Mar 13;10:114. doi: 10.3389/fphys.2019.00114

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Copyright © 2019 Zhang, Polinski, Morrison, Brauner, Farrell and Garver.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Erythrocyte oxygen transport capabilities of PRV infected Atlantic salmon. Bar and whisker plots (bar = 25–75 percentile; whiskers = min–max; line = median; plus = mean; n = 8) of five blood associated indices measured at 4 discrete sampling events. Significant difference (^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.001) in mean value between blood control injected (BC) and PRV injected (PRV) treatment groups are indicated at each time point as determined by uncorrected Fisher’s LSD comparison tests. Significance (p < 0.05) following family-wise p-value multiplicity adjustment (Bonferroni, Sidak, Holm–Sidak tests; α = 0.05) is indicated in bold. (A–E) Data collected from fish that did not undergo IRAP. (F) Data collected from fish immediately after IRAP. Hb, hemoglobin; Hb_21%O2, Hb saturation at 21% oxygen; P₅₀, partial pressure at 50% oxygen saturation.