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. 2019 Feb 13;3(4):716–733. doi: 10.1210/js.2018-00228

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Copyright © 2019 Endocrine Society

This article has been published under the terms of the Creative Commons Attribution Non-Commercial, No-Derivatives License (CC BY-NC-ND; https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Figure 2. — Bmal1 KO females have normal LH response to GnRH, but heightened LH response to kisspeptin. (A) LH values before and after exposure to 1 µg/kg GnRH (n = 6; two-way ANOVA, effect of time; F_1,10 = 88.88, P < 0.0001; Sidak multiple comparisons test). (B) LH values before and after exposure to 30 nmol of kiss-10 (n = 6; two-way ANOVA significant for time and genotype interaction; F_1,10 = 8.4, P = 0.0159; Sidak multiple comparisons test). Different letters indicate significantly different groups (P < 0.05).