Table 1.
Physiological and hemodynamic parameters
| Group | Gestational Age | Fetal Heart Rate, beats/min | Mean UA Velocity, mm/s | Peak UA Velocity, mm/s | UA Blood Flow, ml/min |
|---|---|---|---|---|---|
| Control | E15.5 | 184 (CI: 170–198)*† | 25 (CI: 20–30) | 56 (CI: 47–65) | 0.09 (CI: 0.07–0.11)† |
| cART | E15.5 | 215 (CI: 194–236) | 24 (CI: 17–31) | 52 (CI: 35–69) | 0.07 (CI: 0.05–0.09)‡ |
| Control | E17.5 | 211 (CI: 195–227) | 26 (CI: 23–29) | 57 (CI: 50–64) | 0.12 (CI: 0.10–0.14) |
| cART | E17.5 | 232 (CI: 206–258) | 38 (CI: 21–55) | 78 (CI: 46–110) | 0.15 (CI: 0.09–0.21) |
Data are presented as means and 95% confidence interval (CI) values. cART, combination antiretroviral therapy; E15.5, embryonic day 15.5; E17.5, embryonic day 17.5; UA, umbilical artery.
P < 0.01 compared with cART-treated fetuses at E15.5;
P < 0.01 compared with control fetuses at E17.5;
P < 0.01 compared with cART-treated fetuses at E17.5 (as determined by two-way ANOVA followed by a post hoc t-test).