Table 2.

Measurements of the fetoplacental arterial tree

Group	Gestational Age	Vascular Depth, mm	Vascular Span, mm	Vascular Volume, mm3	No. Vessel Segments
Control	E15.5	1.5 (CI: 1.4–1.6)a	6.8 (CI: 6.6–7.0)	3.4 (CI: 2.8–4.0)a,e	3,500 (CI: 2,900–4,100)
cART	E15.5	1.4 (CI: 1.2–1.6)b	6.7 (CI: 6.5–6.9)	2.6 (CI: 2.1–3.1)b	4,200 (CI: 3,400–5,000)
Control	E17.5	1.8 (CI: 1.7–1.9)c	7.0 (CI: 6.8–7.2)d	5.0 (CI: 4.3–5.7)f	3,300 (CI: 2,800–3,800)d
cART	E17.5	1.6 (CI: 1.5–1.7)	6.6 (CI: 6.5–6.7)	3.6 (CI: 2.9–4.3)	4,500 (CI: 4,000–5,000)

Data are presented as means and 95% confidence interval (CI) values. cART, combination antiretroviral therapy; E15.5, embryonic day 15.5; E17.5, embryonic day 17.5.

^aP < 0.001 compared with control fetuses at E17.5;

^bP < 0.05 compared with cART-treated fetuses at E17.5;

^cP < 0.05 compared with cART-treated fetuses at E17.5;

^dP < 0.001 compared with cART-treated fetuses at E17.5;

^eP < 0.05 compared with cART-treated fetuses at E15.5;

^fP < 0.005 compared with cART-treated fetuses at E17.5 (as determined by a two-way ANOVA followed by a post hoc t-test).