Fig. 7.

The EP2 agonist inhibits PBMC cytokine production in ACLF. Isolated PBMCs from 8 subjects per group were stimulated with LPS in the presence of butaprost (50 μM) or DMSO for 72 h in vitro. The effect of butaprost on cytokine production was determined by the multiplex human cytokine assay (supernatants). Statistical analyses were performed using the Wilcoxon signed-rank test. *p < 0.05, **p < 0.01