Table 3.

Circadian analysis of mean arterial pressure, systolic blood pressure, diastolic blood pressure, heart rate, and activity from control and MatSep rats fed an HFD for 17 wk

	Control			MatSep
	Mesor	Amplitude	Phase	Mesor	Amplitude	Phase
Mean arterial pressure, mmHg
8 wk	105 ± 1	5.5 ± 0.9	17.1 ± 0.7	104 ± 1	5.8 ± 1.0	16.9 ± 0.3
17 wk	104 ± 1	3.6 ± 0.4‡	16.2 ± 0.9‡*	101 ± 3	2.7 ± 0.2‡	16.0 ± 0.2‡*
Systolic blood pressure, mmHg†
8 wk	125 ± 0.9	5.9 ± 0.9	17.0 ± 0.4	123 ± 1.0	6.4 ± 0.9	16.9 ± 0.3
17 wk	126 ± 1.2	4.0 ± 0.6	16.1 ± 0.7	123 ± 3.2	2.6 ± 0.2	15.9 ± 0.5
Diastolic blood pressure, mmHg†
8 wk	87 ± 1.5	5.7 ± 0.6	15.7 ± 0.5	85 ± 1.2	6.3 ± 0.8	19.7 ± 0.2
17 wk	85 ± 1.2	3.9 ± 0.5	14.5 ± 0.7	82 ± 2.5	3.5 ± 0.2	18.6 ± 0.2
Heart rate, beats/min†
8 wk	375 ± 10	58.1 ± 1.3	16.1 ± 0.4	373 ± 6	71.4 ± 4.9	16.1 ± 0.3
17 wk	334 ± 7*	60.4 ± 1.6‡*	15.5 ± 0.3‡*	326 ± 3*	59.6 ± 3.1‡*	15.6 ± 0.3‡*
Locomotor activity (arbitrary activity units)†
8 wk	3.5 ± 0.3	5.3 ± 0.4	17.6 ± 0.2	3.3 ± 0.3	5.3 ± 0.5	17.6 ± 0.2
17 wk	2.7 ± 0.3‡*	4.7 ± 0.6‡*	17.3 ± 0.3	2.3 ± 0.2‡*	3.8 ± 0.5‡*	17.3 ± 0.1

Values are means ± SE. Circadian analysis of mean arterial pressure, systolic blood pressure, diastolic blood pressure, heart rate, and activity from control and maternal separation (MatSep) rats fed a high-fat diet (HFD) for 17 wk. n = 6 for control and 5 for MatSep. Two-way ANOVA:

^‡P_Time < 0.05 vs. 8 weeks HFD,

^*P_Subjects < 0.05 vs. 8 weeks HFD,

^†P_Interaction < 0.05 (systolic blood pressure: mesor in control; diastolic blood pressure: amplitude in control and MatSep; heart rate: mesor in control and MatSep; locomotor activity: amplitude in control and MatSep).