Table 1.

Glucose tolerance test in 12- to 14-wk-old LZR and OZR

Group	n	Age, days	Body Weight, g	Time to Peak, min	AUC, mg/dl × 3 h
LZR	11	90.5 ± 0.7	296.1 ± 6.4	15.4 ± 0.8	333.3 ± 40.2
OZR	12	91.2 ± 0.8	471.7 ± 10.7*	19.2 ± 0.8*	523.2 ± 59.5*

Data are expressed as means± SE; n, number of rats. Age and weight were determined the morning of the glucose tolerance test (Fig. 2). Area under the curve (AUC) was measured as the difference from baseline in 5-min increments from −15 to 165 min in relation to the injection of glucose. LZR, lean Zucker rats; OZR, obese Zucker rats.

^*P < 0.05, unpaired t-tests.