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Anti-biofilm agents derived from natural plants and its potential mechanisms. The inhibition of biofilm formation mainly due to serval aspects including the suppression of microbial adhesion and attachment, the inhibition of polymer matrix and ECM generation and interference with bacterial coaggregation and QS network. QS, quorum sensing; SrtA, sortase A; SpA, Staphylococcal protein A; ECM, extracellular matrix; AIP, autoinducer peptide; AHL, autoinducer acylhomoserine lactone
