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. Author manuscript; available in PMC: 2020 Mar 15.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2018 Nov 29;103(4):922–934. doi: 10.1016/j.ijrobp.2018.11.016

Table D.

Transcription factors and culture conditions used for hepatocyte differentiation

Transcription factors Growth factors Use of serum Additional factors Induced factors Reference
Sox 17, HEX, HNF4α Activin A, BMP4, HGF Yes Oncostatin M, Dexamethasone, ITS GATA6, Sox17, HNF4α Takayama et al. [56]
FoxA2, GATA4, Hex, C/EBPα EGF, BMP, bFGF, EGF, NGF, TGFβ, HGF No Oncostatin M, Ratinoic acid, dexamethasone, ITS (Insulin, transferrin, selenium) Tomizawa et al. [51]
N/A BMP, Activin A, FGF2, HGF No Oncostatin Si-tayeb et al. [58]
N/A Activin A, FGF-4, HGF, BMP2, BMP4, Yes Oncostatin, dexamethasone Ma et al. [57] Duan et al [89]