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. 2019 Mar 13;10:148. doi: 10.3389/fendo.2019.00148

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Copyright © 2019 Landomiel, De Pascali, Raynaud, Jean-Alphonse, Yvinec, Pellissier, Bozon, Bruneau, Crépieux, Poupon and Reiter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mutation-induced receptor bias at the FSHR. Mutations can lead to biased signal transduction at the FSHR upon exposure to fully glycosylated FSH (FSH24). Green, Gs-biased mutants; purple, β-arrestin-biased mutant.