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A: Distribution of non-HLA DR-DQ genetic risk scores in all 4,414 DR3/DR4-DQ8 or DR4-DQ8/DR4-DQ8 children stratified into FDR children (red) and GP children (blue). B: Distribution of non-HLA DR-DQ genetic risk scores in 317 DR3/DR4-DQ8 or DR4-DQ8/DR4-DQ8 children who developed multiple islet autoantibodies. P values were calculated using the two-sided Mann-Whitney U test.
