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. 2019 Jan 17;68(4):847–857. doi: 10.2337/db18-0882

Table 1.

Study characteristics by first-degree relative status

Variable FDR children (n = 423) GP children (n = 4,149)
Males 200 (47.3) 2,082 (50.2)
HLA genotype
 DR3/4-DQ8 280 (66.2) 2,755 (66.4)
 DR4-DQ8/DR4-DQ8 143 (33.8) 1,394 (33.6)
Country
 U.S. 194 (45.9) 1,750 (42.2)
 Finland 51 (12.1) 792 (19.1)
 Germany 92 (21.7) 209 (5.0)
 Sweden 86 (20.3) 1,398 (33.7)
First-degree relative with T1D
 None 0 (0.0) 4,149 (100.0)
 Mother 146 (34.5) 0 (0.0)
 Father 180 (42.6) 0 (0.0)
 Sibling 79 (18.7) 0 (0.0)
 Multiplex 18 (4.3) 0 (0.0)
Outcome events
 One or more islet  autoantibodies 85 (20.1) 415 (10.0)
 Multiple islet autoantibodies 69 (16.3) 255 (6.1)
 First-appearing IAA 51 (12.1) 227 (5.5)
 First-appearing GADA 46 (10.9) 250 (6.0)
 Diabetes 47 (11.1) 145 (3.5)
Genetic risk score available 408 (96.5) 4,006 (96.6)

Data are n (%).