Table 1.
Statistical findings of BLL and P5N-related variables for patients and controls analyzed by unpaired t-test
Variable | Study subjects | Mean | Range | SD | Mean difference | t | P | |
---|---|---|---|---|---|---|---|---|
Min. | Max. | |||||||
BLL (μg/dL) | Patients | 35.89 | 26 | 48.4 | 6.41 | 27.32 | 23.16 | <0.001 |
Controls | 8.57 | 3.2 | 15.7 | 3.42 | ||||
P5N enzymatic activity (μmol uridine/h) | Patients | 3.8 | 1.7 | 5.0 | 1.0 | 7.2 | 18.7 | <0.001 |
Controls | 10.8 | 7.0 | 14.0 | 2.1 | ||||
P5N protein amount | Patients | 25.4 | 16.0 | 45.0 | 7.0 | 14.9 | 11.7 | <0.001 |
Controls | 10.4 | 6.0 | 17.0 | 2.7 | ||||
Purine/pyrimidine ratio in red cells | Patients | 14.3 | 13.0 | 15.3 | 0.6 | 2.7 | 9.2 | <0.001 |
Controls | 17.0 | 15.0 | 20.0 | 1.6 |
BLL: blood lead level; P5N: pyrimidine 5′-nucleotidase; SD: standard deviation, t: the size of the difference relative to the variation of samples