| 6 months earlier |
Hospitalization due to severe symptomatic aortic stenosis (November 2016): uncomplicated transcatheter aortic valve implantation (TAVI). Cardiac biomarkers remained after TAVI within the normal limits (CK 96 U/L, CK-MB 17 U/L) |
| Day 1 |
Patient presents to our department with fatigue, pleuritic chest pain, dyspnoea at rest, non-productive cough, and low degree fever (May 2017) |
| Chest X-ray and computed tomography showed a minimal left pleural effusion. Values of leucocytes and C-reactive protein (CRP) were increased. An antibiotic treatment with clarithromycin and piperacillin/tazobactam on the presumption of an acute bronchitis and ibuprofen to control chest pain were started |
| Day 2 |
A transoesophageal echocardiography was performed to exclude any presence of endocarditis. It showed a TAVI bioprosthesis with normal opening movement with the presence of a low paravalvular leak (Grade 1) |
| Day 7 |
Values of leucocytes and CRP were increased. The antibiotic therapy was changed to meropenem and vancomycin |
| Day 8 |
The patient’s blood cultures and other examinations in medical microbiology and virology such as bacterial, viral, fungal, and parasitic infections were normal |
| Day 11 |
The patient developed high fever (38.5°C), increased pleuritic chest pain and malaise. The leucocytes and CRP arrived at their peak. We changed the antibiotic therapy to daptomycin, fosfomycin, and ceftazidime |
| Day 12 |
A repeated echocardiographic examination showed a new small pericardial effusion (3 mm measured at end-diastole) extending to the right ventricular apex without signs of tamponade |
| Day 15 |
Cardiac magnetic resonance imaging and fluorodeoxyglucose-positron emission tomography with computed tomography were performed. Diagnosis: post-cardiac injury syndrome |
| Treatment with colchicine 0.5 mg, prednisone 20 mg, and ibuprofen 800 mg daily |
| Day 23 |
The patient reported clinical improvement in the following days and CRP value continuously decreased. The patient was discharged |
| 3 months later |
At 3 months after discharge the patient had no symptoms. CRP had remained <5 mg/L |