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. 2018 Sep 28;2(4):yty107. doi: 10.1093/ehjcr/yty107
Time Events
6 months earlier Hospitalization due to severe symptomatic aortic stenosis (November 2016): uncomplicated transcatheter aortic valve implantation (TAVI). Cardiac biomarkers remained after TAVI within the normal limits (CK 96 U/L, CK-MB 17 U/L)
Day 1 Patient presents to our department with fatigue, pleuritic chest pain, dyspnoea at rest, non-productive cough, and low degree fever (May 2017)
Chest X-ray and computed tomography showed a minimal left pleural effusion. Values of leucocytes and C-reactive protein (CRP) were increased. An antibiotic treatment with clarithromycin and piperacillin/tazobactam on the presumption of an acute bronchitis and ibuprofen to control chest pain were started
Day 2 A transoesophageal echocardiography was performed to exclude any presence of endocarditis. It showed a TAVI bioprosthesis with normal opening movement with the presence of a low paravalvular leak (Grade 1)
Day 7 Values of leucocytes and CRP were increased. The antibiotic therapy was changed to meropenem and vancomycin
Day 8 The patient’s blood cultures and other examinations in medical microbiology and virology such as bacterial, viral, fungal, and parasitic infections were normal
Day 11 The patient developed high fever (38.5°C), increased pleuritic chest pain and malaise. The leucocytes and CRP arrived at their peak. We changed the antibiotic therapy to daptomycin, fosfomycin, and ceftazidime
Day 12 A repeated echocardiographic examination showed a new small pericardial effusion (3 mm measured at end-diastole) extending to the right ventricular apex without signs of tamponade
Day 15 Cardiac magnetic resonance imaging and fluorodeoxyglucose-positron emission tomography with computed tomography were performed. Diagnosis: post-cardiac injury syndrome
Treatment with colchicine 0.5 mg, prednisone 20 mg, and ibuprofen 800 mg daily
Day 23 The patient reported clinical improvement in the following days and CRP value continuously decreased. The patient was discharged
3 months later At 3 months after discharge the patient had no symptoms. CRP had remained <5 mg/L