Table III:
Functional connectivity studies – adults born preterm
| Author | Population | Age at scan | Age at birth (preterm) |
Method | Summary of findings |
|---|---|---|---|---|---|
| Scheinost et al.25 | 21 preterm 19 term | 20y | 28.2wks PMA | Voxel-wise | •Adults born preterm showed increased whole brain connectivity in left and right temporal parietal language regions compared with adults born at term |
| Constable et al.24 | 19 preterm 19 term | 20y | 28.2wks PMA | Voxel-wise | •In adults born preterm, the left cerebellum showed increased connectivity compared with adults born at term •Connectivity from this region was increased to bilateral inferior frontal gyrus in adults born preterm and was positively correlated with language scores for adults born preterm |
| Bäuml et al.29 | 95 preterm 83 term | 26.5y | 30.8wks PMA | ICA | •For adults born preterm compared with adults born at term, overlapping regions of greater functional connectivity and reduced gray matter volume were found in language regions of the superior temporal gyrus, caudate, and thalamus. |
| Finke et al.28 | 33 preterm 32 term | 26.5y | 30.5wks PMA | ICA | •Adults born preterm have both greater and weaker connectivity in parietal attention and visual networks compared with adults born at term •Changes were correlated with visual working memory in the same direction of connectivity differences |
| White et al.26 | 29 preterm 23 term | Preterm: 27.6y Term: 28.6y | <33wks PMA | ICA | •Adults born at term had significantly reduced between-network connectivity, particularly alongside those that included thalamo-cortical connections •No differences in spatial focus and spectral power were observed |
PMA, postmenstrual age.