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. Author manuscript; available in PMC: 2019 Mar 20.
Published in final edited form as: Dev Med Child Neurol. 2016 Mar;58(Suppl 4):28–34. doi: 10.1111/dmcn.13043

Table III:

Functional connectivity studies – adults born preterm

Author Population Age at scan Age at birth
(preterm)
Method Summary of findings

Scheinost et al.25 21 preterm 19 term 20y 28.2wks PMA Voxel-wise •Adults born preterm showed increased whole brain connectivity in left and right temporal parietal language regions compared with adults born at term
Constable et al.24 19 preterm 19 term 20y 28.2wks PMA Voxel-wise •In adults born preterm, the left cerebellum showed increased connectivity compared with adults born at term
•Connectivity from this region was increased to bilateral inferior frontal gyrus in adults born preterm and was positively correlated with language scores for adults born preterm
Bäuml et al.29 95 preterm 83 term 26.5y 30.8wks PMA ICA •For adults born preterm compared with adults born at term, overlapping regions of greater functional connectivity and reduced gray matter volume were found in language regions of the superior temporal gyrus, caudate, and thalamus.
Finke et al.28 33 preterm 32 term 26.5y 30.5wks PMA ICA •Adults born preterm have both greater and weaker connectivity in parietal attention and visual networks compared with adults born at term
•Changes were correlated with visual working memory in the same direction of connectivity differences
White et al.26 29 preterm 23 term Preterm: 27.6y Term: 28.6y <33wks PMA ICA •Adults born at term had significantly reduced between-network connectivity, particularly alongside those that included thalamo-cortical connections
•No differences in spatial focus and spectral power were observed

PMA, postmenstrual age.