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. 2019 Mar 20;14(3):e0213665. doi: 10.1371/journal.pone.0213665

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Fig 5 — A) Time evolution of glucose G(t) (in mg/dL). The blue curve corresponds to u_I(t) obtained by solving the ReMF problem. The red curve corresponds to u_I(t) and u_G(t) obtained by solving the ReMF problem using the dual drug therapy. The green curve corresponds to u_I(t) and u_G(t) obtained by solving the ReME problem using the two-drug-therapy. B) Time evolution of the insulin infusion rate u_I(t) (in mg/dL). Color code is consistent with A. C) The cumulative insulin supply r_I(t) as a function of time t. D) Time evolution of the glucagon infusion rate u_G(t) (in mg/dL). E) The cumulative glucose supply r_G(t) as a function of time t.