Table 1. 2-nonanone avoidance assay.
Wild type, mutants and transgenic animals are examined for avoiding 100% 2-nonanone as previously described (Troemel et al., 1997 and S1 Fig). Avoidance Index was calculated as described in S1 Fig. The avoidance in each genotype is represented by the average avoidance index of individual assays. n = 2–4 assays each genotype, 75–100 animals tested in each assay, mutants and transgenic animals are compared with wild-type animals or the non-transgenic siblings tested on the same days with student’s t test, Mean ± SEM.
| Strain | Strain information | Avoidance Index Mean ± SEM |
p value |
|---|---|---|---|
| Wild type | -0.97 ± 0 | ||
| QS4 | ASK-killed | -0.959 ± 0.007 | P > 0.05 |
| Wild type | -0.955 ± 0.0144 | ||
| PY7505 | ASI-killed | -0.921 ± 0.0138 | P > 0.05 |
| Wild type | -0.987 ± 0.012 | ||
| CX3831 | AWB-killed | -0.482 ± 0.106 | P = 0.041 |
| Wild type | -0.965 ± 0.005 | ||
| FX02984 nlp-7(tm2984) |
Neuropeptide NLP-7 | -0.992 ± 0.007 | P > 0.05 |
|
ZC1552 Pglr-1::TeTx ntg |
-0.845 ± 0.035 | ||
|
ZC1552 Pglr-1::TeTx tg |
Blocking synaptic release from command interneurons & some motor neurons | -0.875 ± 0.019 | P > 0.05 |
| Wild type | -0.984 ± 0.004 | ||
| DR40 daf-1(m40) |
Type I TGF-β receptor | -0.915 ± 0.025 | P > 0.05 |
| Wild type | -0.96 ± 0.020 | ||
| ZC2393 Pttx-3::twk-18(gf) |
Expressing twk-18(gf) in AIY | -0.915 ± 0.005 | P > 0.05 |
| Wild type | -0.825 ± 0.075 | ||
| ZC1451 Pnmr-1::TeTx |
Blocking synaptic release from command interneurons | -0.879 ± 0.0003 | P > 0.05 |
| Wild type | -0.972 ± 0.002 | ||
|
ZC1952 Pttx-3::TeTx |
Blocking synaptic release from AIY interneurons | -0.925 ± 0.020 | P > 0.05 |
| Wild type | -0.933 ± 0.003 | ||
| OH8 ttx-3(mg158) |
Disrupting development of AIY interneurons | -0.966 ± 0.013 | P > 0.05 |
| Wild type | -0.98 ± 0.019 | ||
| VC48 kpc-1(gk8) |
Reduction of peptides processed by KPC-1 | -0.81 ± 0.005 | P = 0.014 |
| Wild type | -0.785 ± 0.015 | ||
| CX12330 Psre-1::TeTx |
Blocking synaptic release from ADL | -0.963 ± 0.003 | P = 0.007 |
| Wild type | -0.87 ± 0.030 | ||
| CB1372 daf-7(e1372) |
TGF-β ligand | -0.805 ± 0.055 | P ≥ 0.4078 |
| Wild type | -0.90 ± 0 | ||
| RB2302 daf-7(ok3125) |
TGF-β ligand | -0.83 ± 0.030 | P ≥ 0.144 |