Table 1. Mutations of the gene expression fold change (FC) over wildtype.

Overexpression FC	2	4	8	16	32
Knockout FC	0.001
Knockdown FC	1/2	1/4	1/8	1/16	1/32

For knockout, the fold change is set as 0.001, because 0 has no logarithm, which will generate error for calculation of the target gene expression change.