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. 2015 Jun 15;2015(6):CD007402. doi: 10.1002/14651858.CD007402.pub3
Study Drug Concentration Quantity Frequency Estimated daily dose of topical NSAID
Joussellin 2003 Diclofenac 1% Plaster 1 180 mg epolamine salt, 140 mg Na salt
Li 2013 Diclofenac 1% Plaster 2 360 mg epolamine salt, 280 mg Na salt
Rowbotham 2003 Diclofenac 1% Plaster 2 360 mg epolamine salt, 280 mg Na salt
Saillant 1998 Diclofenac 1% Plaster 1 180 mg epolamine salt, 140 mg Na salt
Coudreuse 2010 Diclofenac 1% Plaster 1 180 mg epolamine salt, 140 mg Na salt
Klainguti 2010 Diclofenac 1% Plaster 1 180 mg epolamine salt, 140 mg Na salt
Predel 2004 Diclofenac Plaster 2 280 mg Na salt
Predel 2012 Diclofenac 2.32% 5 cm ribbon/˜ 2 g 2 or 3 92‐138 mg (?Na equiv) as diethylamine salt
Predel 2013b Diclofenac 1.16% 2 g 4 92 mg (?Na equiv) as diethylamine salt
Predel 2013a Diclofenac 4% 4‐5 sprays 3 96‐120 mg Na salt
Costantino 2011 Diclofenac 1% Plaster 1 180 mg epolamine salt, 140 mg Na salt
Fioravanti 1999 Diclofenac 5 g 3 195 mg epolamine salt
Gallacchi 1990 Diclofenac 1% 2 g 4 80 mg
González de Vega 2013 Diclofenac 1% 6 cm, 2g 3 60 mg
Hoffmann 2012 Diclofenac 1% Plaster 1 180 mg epolamine salt, 140 mg Na salt
Hofman 2000 Diclofenac 1% 2 cm 4 probably 30‐40 mg Na salt
Jenoure 1997 Diclofenac 1% Plaster 2 360 mg epolamine salt, 280 mg Na salt
Mahler 2003 Diclofenac 5 g 3 195 mg epolamine salt
NCT01255423 Diclofenac 1% 4
NCT01272934 Diclofenac 1% 4
NCT01272947 Diclofenac 1% 4
Spacca 2005 Diclofenac 5 g 3 195 mg epolamine salt
Campbell 1994 Ibuprofen 5% 4 inch ribbon 4 Assume 800 mg
Dreiser 1988 Ibuprofen 5% 4 cm ribbon
 (10 cm for larger joints) 4 Assume up‐800 mg
Ramesh 1983 Ibuprofen 5% 5‐10 cm ribbon 3‐4 Assume 300‐800 mg
Billigmann 1996 Ibuprofen 5% 10 cm, 4 g gel 3 600 mg
Machen 2002 Ibuprofen 5% 3
Picchio 1981 Ibuprofen 10% 3
Whitefield 2002 Ibuprofen 5% 3
Mazières 2005b Ketoprofen Plaster 1 100 mg
Mazières 2005a Ketoprofen Plaster 1 100 mg
Airaksinen 1993 Ketoprofen 5 g 2 125 mg
Dreiser 1989 Ketoprofen 2.5% 5 cm 2 100 mg
Julien 1989 Ketoprofen 2.5% 5 cm 2 100 mg
Noret 1987 Ketoprofen 2.5% 5 cm, 7.5 g 2 375 mg
Curioni 1985 Ketoprofen No details   2
Governali 1995 Ketoprofen 5% 2‐3 g 3 300‐450 mg
Governali 1995 Ketoprofen 1% 2‐3 g 3 60‐90 mg
Gualdi 1987 Ketoprofen 3‐5 cm 2
Kockelbergh 1985 Ketoprofen 2.5% 5 cm 2 100 mg
Parrini 1992 Ketoprofen 15.0% 2 g 3 600 mg
Picchio 1981 Ketoprofen 1% 3
Tonutti 1994 Ketoprofen 5% 2‐3 g 3 300‐450 mg
Ăkermark 1990 Indomethacin 1% 0.5‐1.5 mL 3‐5 12‐60 mg
Aoki 1984 Indomethacin 1% 1 g 3‐4 30‐40 mg
Fujimaki 1985 Indomethacin 1% 1 g 3‐4 30‐40 mg
Sugioka 1984 Indomethacin 1% 1 g 3‐4 30‐40 mg
Aoki 1984 Piroxicam 0.5% 1 g 3‐4 15‐20 mg
Fujimaki 1985 Piroxicam 0.5% 1 g 3‐4 15‐20 mg
Russell 1991 Piroxicam 0.5% 5 mg 4 20 mg
Sugioka 1984 Piroxicam 0.5% 1 g 3‐4 15‐20 mg
Chatterjee 1977 Benzydamine 3% 3
Haig 1986 Benzydamine 3% 6
Linde 1985 Benzydamine 3% 3
Auclair 1989 Niflumic acid 2.5% 10 cm, 5 g 3 375 mg
Dreiser 1990 Niflumic acid 2.5% 10 cm, 5 g 3 375 mg
Curioni 1985 Ibuproxam gel 10% 2
Curioni 1985 Etofenamate No details 2
Diebshlag 1990 Etofenamate 5% 3 g 3 450 mg
Tonutti 1994 Etofenamate 5% 2‐3 g 3 300‐450 mg
Diebshlag 1990 Ketorolac 2% 3 g 3 360 mg
Dreiser 1994 Flurbiprofen Patch   2 80 mg
Gualdi 1987 Flunoxaprofen 3‐5 cm 2
Hofman 2000 Lysine clonixinate 5% 2 cm 4 90 mg
Hosie 1993 Felbinac 3% 2 g 3 180 mg
McLatchie 1989 Felbinac 3% 3 cm 3
Morris 1991 Felbinac 3% 1 cm 3
Sanguinetti 1989 Felbinac 3% 3
Sinniger 1981 Fentiazac 5% Varied according to involved areas 2‐3
Thorling 1990 Naproxen 10% 2‐6
Vecchiet 1991 Meclofenamic acid 5% 10 cm, 4 g 2 400 mg
equiv: equivalent; Na: sodium.