Morris 1991.

Methods	R, DB, PC, parallel groups Gel applied to site of injury 3 times daily for 7 days Assessed at baseline, 7 days at clinic, and daily patient diary
Participants	Acute soft tissue injury (< 3 days) N = 100 (84 analysed for efficacy) M 70, F 14 Mean age 25 years Baseline pain moderate to severe Exclusions: 1 participant in placebo group lost to follow‐up, 15 protocol violations
Interventions	Felbinac gel 3%, 3 x 1 cm daily, n = 41 Placebo gel, n = 43 Ice, joint immobilisation, bandaging and compression allowed No concomitant oral NSAID, occlusive dressing, physiotherapy, or liniments allowed Rescue medication: paracetamol
Outcomes	PGE: 5‐point scale (responder = "good" and "very good") Change in PI: patient diary 10 cm VAS (mean data) Adverse events Withdrawals and exclusions
Notes	Oxford Quality Score: R1, DB2, W1. Total = 4/5
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Low risk	"Randomisation was undertaken at the production facility and a sealed copy of the list supplied to the investigator for reference, only in defined circumstances"
Blinding (performance bias and detection bias) All outcomes	Low risk	"identical tubes and outer boxes", "placebo was a similarly constituted gel"
Incomplete outcome data (attrition bias) All outcomes	Low risk	All relevant participants included in analysis
Size	High risk	< 50 participants per treatment arm