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. 2015 Jun 15;2015(6):CD007402. doi: 10.1002/14651858.CD007402.pub3

Noret 1987.

Methods R, DB, PC parallel groups
Gel applied twice daily for 7 days
Assessment at baseline, 3, 8 days
Participants Minor sports injuries (< 24 hours)
N = 98 (93 analysed)
M 71, F 27
Mean age 29 years
Baseline pain > 60 mm
Interventions Ketoprofen gel 2.5%, 2 x 5 cm daily (= 15 mg), n = 48
Placebo gel, n = 45
No other treatment given
Outcomes PGE: 4‐point scale (responder = "good" and "excellent")
Spontaneous pain: 100 mm VAS (mean data)
Adverse events
Withdrawals
Notes Oxford Quality Score: R1, DB1, W1. Total = 3/5
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described
Allocation concealment (selection bias) Low risk "allocated according to a randomization list and a corresponding code in a sealed envelope"
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Not described
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All participants included in analysis
Size High risk < 50 participants per treatment arm