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. 2015 Jun 15;2015(6):CD007402. doi: 10.1002/14651858.CD007402.pub3

NCT01874626.

Methods R, DB, PC, parallel groups
Participants Acute ankle sprain, Grade I or II ≤ 24 hours. Age ≥ 16 years. Baseline PI ≥ 5/10
N = 305
Interventions Ibuprofen cream 200 mg in 2.7 g cream x 4 daily
 Placebo cream x 4 daily
 Treatment for 7 days
Outcomes PI on movement daily to 7 days
 PGE 7 days
Systemic and local adverse events
Notes Estimated completion January 2014. No results