FIGURE 2.
CTLs slow progression of metastatic osteosarcoma. Balb/cJ mice were injected with 106 K7M2 osteosarcoma cells post-CD8 depletion. Survival was significantly decreased in mice depleted of CD8 cells (dashed line), compared with wild-type mice (solid line). Log-rank (Mantel-Cox) test showed a significant P-value <0.0001. CD8-depleted group had an n = 10, whereas the wild-type K7M2 injected group had an n = 55.
