. 2019 Mar 19;10(2):e00225-19. doi: 10.1128/mBio.00225-19

TABLE 1.

Comparison of primary fibroblast cell analyte levels for C. trachomatis ocular Ba and urogenital E infections^a

Cytokine or chemokine	Fold change in analyte level in CjS cells infected with:		P value	Fold change in analyte level in EcS cells infected with:		P value	Fold change in analyte level in EmS cells infected with:		P value
Cytokine or chemokine	Ba	E	P value	Ba	E	P value	Ba	E	P value
Proinflammatory cytokines
IL-1α	2.45 ± 1.05	21.9 ± 16.24	*0.0132*	2.03 ± 1.17	9.4 ± 4.54	*0.0137*	4.77 ± 0.97	13.49 ± 6.51	*0.0197*
IL-1β	2.58 ± 1.19	10.22 ± 5.66	*0.0077*	5.68 ± 4.57	69.39 ± 89.67	0.0570	5.65 ± 2.91	29.68 ± 8.1	*0.0030*
GM-CSF	1 ± 0	78.4 ± 54.16	*0.0030*	16.68 ± 11.94	32.62 ± 34.67	0.6887	12.19 ± 12.66	15.12 ± 7.83	0.4779
IFN-γ	0.4602 ± 0.7308	1.542 ± 2.037	0.7248	0.1339 ± 0.1313	1.696 ± 0.7026	*0.004*	3.113 ± 4.783	0.3289 ± 0.4524	0.4553
Regulatory T cells/Th2 cytokines
IL-2	13.54 ± 10.23	12.73 ± 11.33	0.8005	12.67 ± 3.083	1 ± 0	*<0.0001*	1.49 ± 1.77	0.71 ± 0.51	0.7713
TARC (CCL17)	15.59 ± 7.76	3.12 ± 2.28	*0.0407*	1.09 ± 0.53	0.96 ± 0.17	0.3411	2.34 ± 0.68	1.15 ± 0.65	0.5980
Chemokines
IP-10 (CXCL10)	1,036 ± 1,239	6.45 ± 3.21	*0.0101*	11.13 ± 10.93	0.68 ± 0.56	0.0509	59.17 ± 89.17	0.21 ± 0.09	*0.0321*
IL-12p70	5.78 ± 3.39	4.23 ± 0.28	0.6334	14.44 ± 3.02	7.79 ± 0.93	*0.0122*	10.25 ± 6.49	1.99 ± 0.71	*0.0411*
MIP-1β	12.83 ± 5.68	1.82 ± 0.88	*0.0099*	13.57 ± 5.36	4.76 ± 3.79	0.1209	2.81 ± 1.89	1.64 ± 0.63	0.5105
IL-8 (CXCL8)	13.25 ± 5.06	52.54 ± 26.65	*0.0100*	7.09 ± 8.07	8.08 ± 9.93	0.9855	13.36 ± 10.17	37.7 ± 28.29	0.1150

The cytokines and chemokines with strain-dependent differences are shown. Data are the same as in Fig. 4 and represent fold changes (with averages and standard deviations for four patients) from levels in uninfected cells. Underlining indicates a trend in the data; boldface italics indicate statistically significant P values.