Table 1:
Characteristics | 82Rubidium | 13N-Ammonia | 15O-water |
---|---|---|---|
Half-life | 78 sec | 9.8 min | 2.4 min |
Extraction fraction* | ~60% | ~80% | ~95% |
Cyclotron on-site | No | Yes | Yes |
Data acquisition | Dynamic, static, gated | Dynamic, static, gated | Dynamic |
Scan duration | 6 min | 20 min | 5 min |
Dose (2-Dimensional PET) | 40-60 mCi | 15-25 mCi | 40 mCi |
Dose (3-Dimensional PET) | 15-20 mCi 30-40 mCi 3D LSO |
15 mCi | 10 mCi |
Interval between doses | 10 min | 30 min | 7 min |
Image interpretation | Yes | Yes | No |
Image quality | Good | Excellent | N/A |
LSO = lutetium oxyorthosilicate; MBF = myocardial blood flow; PET = positron emission tomography
Extraction fraction based on baseline myocardial blood flow (~1 ml/g/min).
Reproduced with permission from Schindler et al3.