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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Pharmacogenomics J. 2018 Sep 20;19(3):295–304. doi: 10.1038/s41397-018-0049-x

Table 1.

Clinical characteristics of INVEST and SPS3

Clinical characteristics INVEST
SPS3
Whites
Hispanics
Whites
Hispanics
Controls N = 431 RHTN cases N = 226 Controls N = 394 RHTN cases N = 143 Controls N = 192 RHTN cases N = 71 Controls N = 239 RHTN cases N = 83
Age 70 ± 10 70 ± 9 66 ± 10 66 ± 10 64 ± 10 63 ± 9 63 ± 11 63 ± 11
Female 184 (43%) 114 (50%) 225 (57%) 87 (61%) 70 (36%) 18 (25%) 98 (41%) 37 (45%)
BMI, mean ± SD 29 ± 6 29 ± 6 28.5 ± 5 30 ± 5** 29 ± 6 31 ± 10 28 ± 4 30 ± 6##
SBP at RHTN classification 126 ± 9 141 ± 17* 124 ± 9 143 ± 18** 126 ± 9 138 ± 14# 122 ± 11 133 ± 14##
DBP at RHTN classification 73 ± 8 76 ± 11* 76 ± 7 84 ± 10** 71 ± 8 73 ± 9 67 ± 10 70 ± 10
Diabetes 64 (15%) 66 (29%)* 51 (13%) 25 (18%) 44 (23%) 25 (35%)# 71 (30%) 33 (40%)
Heart failure 27 (6%) 17 (8%) 6 (2%) 8 (6%)** 1 (1%) 2 (1.4%) 2 (0.9%) 1 (1.2%)
Myocardial infarction 170 (39%) 92 (41%) 35 (9%) 23 (16%) 6 (3%) 8 (11%)# 8 (3%) 2 (2%)
Peripheral vascular disease 40 (9%) 35 (16%)* 34 (9%) 23 (16%)** 4 (2%) 2 (3%) 0 (0%) 2 (2%)
Smoking 204 (47%) 113 (50%) 137 (35%) 44 (31%) 41 (21%) 21 (30%) 18 (8%) 3 (4%)

Continuous variables are expressed as means ± standard deviations (SD), categorical variables are expressed as frequency and percentages

BMI Body mass index, SBP systolic blood pressure, DBP diastolic blood pressure

*

p < 0.05 compared to controlled BP in INVEST Whites

**

p < 0.05 compared to controlled BP in INVEST Hispanics

#

p <0.05 compared to controlled BP in SPS3 Whites

##

p < 0.05 compared to controlled BP in SPS3 Hispanics