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. 2010 Dec 20;13(12):1136–1140. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2010.12.11

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单项血清肿瘤标志物检测(国内)

Detection of the single tumor marker in Serum (domestic)

Biomarker Diagnosis Reference Patients Controls Sensitivity Specificity Accuracy
NSCLC: non-small cell lung cancer; CC: squamous cell carcinoma; adenoCA: adenocarcinoma; SCLC: small cell lung cancer.
CEA SCLC, NSCLC, adenoCA 52 6 754 3 942 47.50% 92.34% 64.03%
CA125 SCLC, NSCLC, adenoCA 42 3 082 1 186 50.11% 80.19% 58.47%
CYFRA21-1 NSCLC, SCC 53 4 142 2 734 57.00% 90.16% 70.19%
TPA NSCLC, SCC 13 1 774 700 50.93% 88.41% 61.54%
SCCAg NSCLC, SCC 8 814 510 49.00% 91.07% 65.20%
NSE SCLC 47 3 857 2 914 39.73% 89.11% 60.98%
ProGRP SCLC 7 503 473 51.48% 94.89% 72.52%
CA19-9 SCLC, NSCLC 19 2 404 2 075 44.00% 93.94% 67.13%
CA153 SCLC, NSCLC 26 2 598 3 110 39.66% 94.11% 69.33%
Ferrtin SCLC, NSCLC 5 749 415 27.90% 86.27% 48.71%
GSF SCLC, NSCLC 0 0 0 0 0 0
M-CSF SCLC, NSCLC 0 0 0 0 0 0
DKK1 SCLC, NSCLC 1 592 192 69.50% 92.20% 85.70%