Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 14;10:178. doi: 10.3389/fgene.2019.00178

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Jones, Lingampally, Dilai, Shrestha, Stripp, Helmbacher, Chen, Chao and Bellusci.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Expression pattern of ETV5-RFP in distal lung epithelium during early development (A) Experimental design: E12.5 Etv5^RFP lung explants were cultured for 40 h and live imaged. (B) Still images showing representative ETV5-RFP expression both globally and in the distal tips (boxes). Arrows indicate increased expression in the tips over time. Scale bar: (Top row) 500 μm; (Bottom row) 125 μm. (C) Example images of a branching tip at three successive time points (a–c), highlighting three regions of dynamic ETV5-RFP expression: the tip (1 and 2), the cleft (3), and the stalk (4 and 5). See text for details. Scale bar: 37 μm. (D) Representative plot of ETV5-RFP expression in three independent regions [(a) tip, (b) stalk and (c) cleft] of a single bud over a period of 40 h (n = 1; a.u. = arbitrary units).