Table 3.
Medication intake, timing, and type in the cases and controls
| Cases, % (n/N) | Controls, % (n/N) | p valuea | |
|---|---|---|---|
| Medication use | |||
| Any medication use during pregnancy | 35 (68/196) | 17 (34/196) | 0.0001 |
| Timing of medication intake among women taking medicationsb | |||
| Any medication use during first trimesterd | 42 (23/55) | 23 (7/31) | 0.1 |
| Any medication use during second trimesterd | 34 (22/65) | 38 (12/32) | 0.7 |
| Any medication use during third trimester | 63 (43/68) | 65 (22/34) | 0.9 |
| Type of medication intake among women taking medicationsb | |||
| ‘Probably safe’ medications onlyc | 62 (42/68) | 65 (22/34) | 0.9 |
| At least one ‘potentially risky’ medicationc | 21 (14/68) | 18 (6/34) | |
| At least one unclassified medicationc | 18 (12/68) | 18 (6/34) | |
The ‘probably safe’ category consisted of A, B1, and B2 classifications and the ‘potentially risky’ category consisted of B3, C, D, and X as per the Australian categorization system (https://www.tga.gov.au/prescribing-medicines-pregnancy-database)
ap values were estimated using the chi-squared test
b‘Among women taking medications’ means the denominator used was only those women who reported taking any medication as opposed to the whole group of women
cMultiple medications were taken by some women and some medications were taken more than once
dFor some women, data from posts were missing in the first and second trimester