Table 4.
Results of ordinal logistic regression for RS2075650, RS2305421, RS10498633, and ABC score.
| Variables | ABC score# | Univariate model | Multivariate model 1* | Multivariate model 2* | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | L | I | H | Unadjusted OR | P | Adjusted OR | P | Adjusted OR | P | |
| RS2075650 | ||||||||||
| AA | 27 | 27 | 21 | 8 | Reference | Reference | Reference | |||
| AG | 2 | 6 | 4 | 7 | 3.615 (1.428, 9.152) |
0.007 | 3.340 (1.306, 8.542) | 0.012 | 2.430 (1.562, 9.217) | 0.192 |
| RS2305421 | ||||||||||
| AA | 13 | 18 | 5 | 3 | Reference | Reference | Reference | |||
| AG | 15 | 13 | 15 | 9 | 2.014 (0.938, 4.323) | 0.073 | 2.136 (0.969, 4.711) | 0.060 | 2.321 (1.041, 5.176) | 0.040 |
| GG | 1 | 4 | 5 | 3 | 4.187 (1.311, 13.383) | 0.016 | 3.896 (1.190, 12.743) | 0.025 | 4.397 (1.326, 14.600) | 0.015 |
| RS10498633 | ||||||||||
| GG | 16 | 14 | 8 | 3 | Reference | Reference | Reference | |||
| GT | 11 | 20 | 16 | 12 | 2.686 (1.275, 5.658) | 0.009 | 2.226 (1.038, 4.773) | 0.040 | 2.375 (1.095, 5.150) | 0.028 |
#ABC score was divided into four grades: N (none), L (low), I (intermediate), H (high).
*Age and one of the three SNPs were included in multivariate model 1; age, APOE ε4 and one of the three SNPs were included in multivariate model 2.