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. 2019 Mar 14;10:486. doi: 10.3389/fmicb.2019.00486

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Copyright © 2019 Pinto, Neves, Souza, Oliveira, Costa, Castro, Mendonça-Souza, Peralta and Teixeira.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The most common pneumococcal capsular types (comprising 50 to 60% of the pneumococcal isolates) according to the clinical source and period of time. Carriage isolates (represented in the upper lines) included strains recovered from nasopharynx or oropharynx specimens while IPD (invasive pneumococcal disease) isolates (represented in the bottom lines) included strains recovered from blood or cerebrospinal fluid. Serotypes colored in green are included in the 10-valent pneumococcal conjugate vaccine (PCV); those colored in yellow are only included in the 13-valent PCV; and those colored in black are not included in any PCV currently available.