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. 2019 Mar 14;10:486. doi: 10.3389/fmicb.2019.00486

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Copyright © 2019 Pinto, Neves, Souza, Oliveira, Costa, Castro, Mendonça-Souza, Peralta and Teixeira.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution over time of capsular types included in the 10-valent pneumococcal conjugate vaccine (PCV10; in green), of those included only in the 13-valent pneumococcal conjugate vaccine (PCV13; in yellow) and of those not included in any PCV currently available [non-vaccine (NV), in black]. (A) Distribution among 355 Streptococcus pneumoniae isolates recovered from asymptomatic carriers. (B) Distribution among 428 S. pneumoniae isolates recovered from patients with IPD. 10-valent PCV includes serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F, and 23F; 13-valent PCV also includes 3, 6A, and 19A.