Table 5.
Distribution of penicillin minimum inhibitory concentration (MIC) levels among Streptococcus pneumoniae, according to the period of time and clinical source.
| Clinical sourcea | MIC50 (μg/ml) |
MIC90 (μg/ml) |
||||||
|---|---|---|---|---|---|---|---|---|
| 1990–1995 | 1996–2002 | 2003–2010 | 2011–2014 | 1990–1995 | 1996–2002 | 2003–2010 | 2011–2014 | |
| Carriage | 0.03 | 0.06 | 0.03 | 0.50 | 0.25 | 0.12 | 2 | 4 |
| IPD | 0.03 | 0.06 | 0.09 | 0.01 | 0.12 | 0.12 | 4 | 0.12 |
aCarriage isolates included strains recovered from nasopharynx or oropharynx specimens while IPD (invasive pneumococcal disease) isolates included those recovered from blood or cerebrospinal fluid.