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. 2018 Apr 13;40(12):967–978. doi: 10.1093/eurheartj/ehy188

Figure 6.

Figure 6

Delta-like homologue 1 is down-regulated in human ischaemic/fibrotic hearts and within the scar of infarcted pigs’ myocardium. (A) qRT-PCR of total delta-like homologue 1 and soluble/cleaved-encoding delta-like homologue 1 mRNA variants from healthy and ischaemic human cardiac (upper panel), and representative western blot of DLK1 in ischaemic patients (lower panel). (B) qRT-PCR of total delta-like homologue 1 and soluble/cleaved-encoding delta-like homologue 1 mRNA variants from sham pigs and from the remote, border and scar tissues of infarcted pigs’ hearts (upper panel) and western blot of delta-like homologue 1 in pigs’ scar lysates (lower panel). Commassie-blue staining is a loading control in A and B. (C) qRT-PCR mRNA quantification of collagen-1a, lysyl oxidase and α-smooth muscle actin.