Table 4.
Summary of recent publications for the detection of proteins using eMIPs. Includes information on the functional monomer used, electrode material, polymerization technique, detection method, and LOD.
Table | Functional Monomer | Electrode Material | EP Technique | Detection Method | LOD | Ref. |
---|---|---|---|---|---|---|
troponin T | pyrrole/pyrrole-3-carboxylic acid | SPCEf | CVi | DPVk | 0.006 ng/mL | [141] |
myoglobin | o-phenylenediamine | SPCEf | CVi | DPVk | 0.5 nM | [143] |
hemoglobin | TBAe | Au | CVi | CAl | 82 nM | [145] |
HER2-ECDa | phenol | AuSPEg | CVi | DPVk | 1.6 ng/mL | [148] |
CA 15-3b | o-aminophenol | AuSPEg | CVi | DPVk | 1.5 U/mL | [149] |
CA 15-3 b | toluidine blue | AuSPEg | CVi | DPVk | 0.1 U/mL | [150] |
PSAc | dopamine | Au | CVi | MOSFETm | 0.1 pg/mL | [158] |
Annexin A3 | Caffeic acid | SPCEf | CPj | SWVn | 0.095 ng/mL | [159] |
S-ovalbumin | pyrrole | GCEh | CVi | DPVk | 2.95 × 10−9 mg/mL | [160] |
Microseminoprotein-beta | Caffeic acid | SPCEf | CPj | SWVn | 0.12 ng/mL | [161] |
Human serum albumin | Bis(2,2′-bithien-5-yl)methane | Au | CVi | DPVk | 0.25 pM | [162] |
CA 15-3b | pyrrole | FTOp | CVi | Potentiometry | 1.07 U/mL | [163] |
CA 15-3b | o-phenylenediamine | AuSPEg | CVi | SWVn | 0.05 U/mL | [164] |
Human serum albumin | scopoletin | Au | CVi | CVi | 56 nM | [157] |
transferrin | scopoletin | Au | CVi | SWVn | - | [154] |
a HER2-ECD—Human Epidermal Growth Factor Receptor 2-Extracellular Domain; b CA 15-3—Cancer Antigen 15-3; c PSA—Prostate -Specific Antigen; d CEA—Carcinoembryonic Antigen; e TBA—2,2′,5,5′-terthiophene-3′-p-benzoic acid; f SPCE—Screen-Printed Carbon Electrode; g AuSPE—Gold Screen-Printed Electrode; h GCE—Glassy Carbon Electrode; i CV—Cyclic Voltammetry; j CP—Constant Potential; k DPV—Differential Pulse Voltammetry; l CA—Chronoamperometry; m MOSFET—Metal Oxide Semiconductor Field-Effect Transistor; n SWV—Square Wave Voltammetry; o EIS—Electrochemical Impedance Spectroscopy; p FTO—Fluorine doped Tin Oxide.