Table 1.
Numbers of patients screened and baseline characteristics of patients enrolled in the therapeutic efficacy study at four sentinel sites in 2016
| Variable | Kibaha | Mkuzi | Mlimba | Ujiji | Overall |
|---|---|---|---|---|---|
| Screened | 158 | 177 | 295 | 333 | 963 |
| Enrolled (%) | 80 (50.6) | 88 (49.7) | 88 (30.3) | 88 (26.4) | 344 (35.7) |
| Age in years, mean (SD)a | 6.5 (2.7) | 5.7 (2.8) | 3.4 (2.3) | 4.6 (2.9) | 5.0 (2.9) |
| Children < five years of age, n (%)† | 29 (36.3) | 36 (40.9) | 66 (75.0) | 58 (65.9) | 189 (54.9) |
| Sex (male), n (%) | 46 (57.5%) | 49 (55.7%) | 49 (55.7%) | 52 (59.1%) | 196 (57.0) |
| Weight (kg), mean (SD)b | 19.1 (5.6) | 17.4 (5.0) | 13.1 (4.3) | 14.9 (5.1) | 16.1 (5.5) |
| Height in cm, median (IQR)c | 114.0 (98.5, 128.3) | 111.0 (92.1, 121.0) | 85.5 (77.0, 99.8) | 97.0 (86.0, 111.8) | 100.0 (85.0, 117.8) |
| Temperature in °C, mean (SD) | 37.8 (1.4) | 37.7 (1.1) | 37.6 (1.3) | 37.7 (1.4) | 37.7 (1.3) |
| Parasitaemia* (95% CI)a | 9403 (5901–14,984) | 32,357 (23,393–44,756) | 27,720 (20,706–37,108) | 41,106 (30,356–55,664) | 24,806 (20,701–29,726) |
°C: degree Celsius; parasitaemia*: geometric mean parasite density (asexual parasites/µl); IQR: interquartile range; n: number of patients; SD: standard deviation; 95% CI : 95% confidence interval. † p < 0.001; athe mean was significantly different between all paired comparison of the sites (p ≤ <0.031) except for Kibaha vs Mkuzi (p = 0.300); bthe mean weight was significantly different between all paired comparison of the sites (p ≤ <0.005) except for Kibaha vs Mkuzi (p = 0.200), and Mlimba vs Ujiji (p = 0.120); cthe mean height was significantly different between all paired comparison of the sites (p < 0.001) except for Kibaha vs Mkuzi (p = 0.138), and Mkuzi vs Ujiji (p = 0.068)