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. 2019 Feb 28;12:45. doi: 10.3389/fnmol.2019.00045

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Copyright © 2019 Kovács, D'Agostino, Diamond and Ari.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of combined administration of KEKS food (20% KEKS and 1% saccharin in standard rodent chow) with IP indomethacin plus IP LPS (10 mg/kg + 50 μg/kg, respectively) on SWD number on the day of 9th KEKS food administration (9K+I+L; group 6). 1K, 1st KEKS food administration; 2K, 2nd KEKS food administration and so on; 9K+I+L, combined administration of KEKS food (K) with i.p. indomethacin (I) and i.p. LPS (L) on the day of 9th KEKS food administration; CON, control; SWD, spike-wave discharge. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, and ^****p < 0.0001.